Located on the Upper East Side of New York City, LUXURGERY© was founded by Dr. Sachin M. Shridharani, who is certified by the American Board of Plastic Surgery. His background includes plastic and reconstructive surgery training at Johns Hopkins Hospital and an Aesthetic Plastic Surgery fellowship at Manhattan Eye, Ear and Throat Hospital. Dr. Shridharani also served as a clinical trial investigator in two pivotal studies evaluating Relfydess.
What Makes Relfydess Different From BOTOX Cosmetic?
Relfydess is a newer botulinum toxin type A product designed for rapid onset and longer-lasting results. BOTOX Cosmetic is onabotulinumtoxinA, a well-established botulinum toxin type A with a long history of clinical use.
Both Relfydess and BOTOX Cosmetic temporarily reduce targeted muscle activity associated with expression lines. Relfydess has been studied and approved internationally for moderate-to-severe frown lines and crow’s feet, while BOTOX Cosmetic has established aesthetic uses across several facial areas.
Relfydess has demonstrated a rapid onset, with up to 39% seeing visible improvement on Day 1 and most noticing results within two to three days. Results can also last up to six months.
BOTOX Cosmetic works on a well-established timeline. At LUXURGERY, initial changes may become noticeable within 24 to 48 hours, with maximal results developing in about seven to 10 days. Results commonly last about three to four months, though duration varies by individual.
Why Would Someone Consider a Newer Neuromodulator Like Relfydess?
A newer neuromodulator such as Relfydess may appeal to patients interested in exploring alternative formulations of botulinum toxin type A or those seeking a potentially faster onset of visible improvement.
BOTOX Cosmetic, by comparison, is a well-established neuromodulator with an extensive history of aesthetic use and a typical duration of about three to four months.
Your goals, treatment history, desired onset speed, and preferred duration of results all play an important role in determining which option may be most appropriate.
Is Relfydess Available in the United States?
Availability depends on regulatory approval status. As of now, BOTOX Cosmetic is fully FDA-approved and widely available in the United States, including at LUXURGERY in New York, NY.
Relfydess is a newer neuromodulator approved in dozens of international markets and launched in more than 20 countries following regulatory review, but it is not yet broadly available for aesthetic use in the United States as of 2026.
Compare Your Neuromodulator Options in New York, NY
Neuromodulators are not interchangeable, and differences in formulation, onset, and duration can meaningfully impact your treatment experience. At LUXURGERY in New York City, Dr. Shridharani will help determine which FDA-approved injectable option best aligns with your aesthetic goals. Contact us today at 212.508.0000.
